We had a great time at the American Society of Human Genetics in snowy Denver! Our group presented one talk and four posters (two of which received the Reviewer's Choice Award!). Ryan gave a talk on the lab's recent collaboration with the Lareau Lab at MSK on HHV6 integration in the human genome. Alex Han presented an abstract on his recent work showing the importance of human genetic diversity in genic intolerance metrics. Vida and rotation student Dan Brock presented on our recent discovery of a new retinal detachment gene. Finally, Chloe Sands was co-first author with our AstraZeneca collaborators on our recent discovery of ITSN1 as a novel Parkinson's disease gene!
This grant will provide the lab $200,000 over two years to pursue a project on “Genetic resilience to Aging." Started in 2021, the goal of Impetus Grants, is to fund ideas in the that are typically ignored by traditional funders. Since then, they have deployed more than $24 million into science, supporting a number of aging clinical trials, biomarkers, novel tools, and model organisms. This round of funding was launched in August of 2023 with Hevolution and Rosenkranz foundations to focus on high-risk high-reward studies in aging science.
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High-Risk, High-Reward Research program, supported by the Common Fund at the National Institutes of Health, awards new research grants to support "highly innovative scientists who propose visionary and broadly impactful meritorious behavioral and biomedical research projects." The award will provide $250,000 in direct research costs annually for up to five years and will help us develop a high-throughput framework for identifying convergent mechanisms among neurodevelopmental disease risk genes.
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© Ryan Dhindsa, 2024